WebScott L. Harbeson, Roger D. Tung, in Annual Reports in Medicinal Chemistry, 2011 1 Introduction. Deuterated compounds have been widely studied in nonclinical settings and have seen broad application as metabolic or pharmacokinetic (PK) probes both in vitro and in vivo [1,2].Depending upon a given compound's route of metabolism and the location of … WebMar 13, 2014 · In the case of the team’s organic solar cells, deuteration turns out to have a negative impact, decreasing the devices’ electrical efficiency. But the ORNL researchers note that other organic electronics such as organic spintronics or light emitting diodes (OLEDs) could benefit from deuterium’s effects. “Overall, deuterating polymers ...
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Webverb deu· ter· ate ˈdü-tə-ˌrāt also ˈdyü- deuterated; deuterating transitive verb : to introduce deuterium into (a compound) deuteration ˌd (y)ü-tə-ˈrā-shən noun Word History First … A deuterated drug is a small molecule medicinal product in which one or more of the hydrogen atoms contained in the drug molecule have been replaced by its heavier stable isotope deuterium. Because of the kinetic isotope effect, deuterium-containing drugs may have significantly lower rates of metabolism, and hence a longer half-life. smallest breed of owl
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Webdeuterate ( ˈdjuːtəˌreɪt) vb (Chemistry) chem to treat or combine with deuterium Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014 deu•ter•ate (ˈdu təˌreɪt, ˈdyu-) v.t. -at•ed, -at•ing. to add deuterium to (a chemical compound). WebAn inner ear infection causes parts of your inner ear to become irritated or inflamed. As a result, your hearing and balance can be affected. Inner ear infections can happen if you catch a cold or have the flu. They can also develop when a middle ear infection moves into your inner ear. Northeast Ohio 216.444.8500 Appointments & Locations Webdeuterate ( ˈdjuːtəˌreɪt) vb (Chemistry) chem to treat or combine with deuterium Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014 deu•ter•ate (ˈdu təˌreɪt, ˈdyu-) v.t. -at•ed, -at•ing. to add deuterium to (a chemical compound). smallest boxwood plants