WebSep 12, 2013 · English: Reaction Schemes of the Gassman Oxindole Synthesis. Deutsch: Reaktionsgleichung der Gassman-Oxindol-Synthese. Date: 12 September 2013: Source: Own work: Author: Andel (talk) Public domain Public domain false false: Web3.6 Gassman Oxindole Synthesis 133. 3.7 Larock Indole Synthesis 143. 3.8 Matinet Dioxindole Reaction 167. 3.9 Mori-Ban Indole Synthesis 175. 3.10 Sandmeyer Isatin Synthesis 187. 3.11 Sommelet-Hauser Rearrangement 197. 3.12 Stolle Oxindole Synthesis 207. Chapter 4 Furans and Ox azoles 213. 4.1 Nierenstein Reaction 214. 4.2 …
General method for the synthesis of oxindoles Journal of …
WebJan 1, 2014 · The Gassman indole synthesis involves a one-pot process in which a hypohalite, a β-carbonyl sulfide derivative, and a base are added sequentially to an … WebSep 15, 2010 · This reaction is a multistep process (but a one‐pot reaction) for preparing oxindole with an electron‐withdrawing group involving sequential treatment of aniline … buy used license plates
GASSMAN Oxindole synthesis - Big Chemical Encyclopedia
WebConversion of Ketones to Cyanohydrins: Benzophenone Cycanohydrin intermediate: O-(trimethylsilyl) benzophenone cyanohydrin product: Benzophenone cyanohydrin product: Cyclohexanone cyanohydrin product: Cyclooctanone cyanohydrin product: Fluorenone cyanohydrin product: tert-Butyl phenyl ketone cyanohydrin product: p … WebJan 1, 2024 · Following Gassman Synthesis, Pfizer Central Research Group synthesized oxindole with slight modification in the original procedure; that is, using oxalyl chloride to activate the sulfoxide to aid the formation of the key N–S bonded intermediate [22]. WebA practical modification of the Gassman 3-(methylthio)oxindole synthesis is reported. In our method, substituted anilines and 2-(methylthio)acetamide were reacted under mild reaction conditions, in the presence of N-chlorophthalimide as a chlorinating agent to give α-amidosulfides, which, in the next step of the process, were cyclized to give 3 … certified nanny training