WebWe investigated the transcriptomic changes in the shoot apices during floral transition in Arabidopsis mutants of two closely related splicing factors: AtU2AF65a (atu2af65a) and AtU2AF65b (atu2af65b). The atu2af65a mutants exhibited delayed flowering, while the atu2af65b mutants showed accelerated flowering. The underlying gene regulatory …
PTBP3 polypyrimidine tract binding protein 3 - NIH …
WebHere we show that genes encoding critical presynaptic proteins are transcribed at a detectable level in both neurons and nonneuronal cells. However, in nonneuronal cells, the splicing of 3′-terminal introns within these genes is repressed by the polypyrimidine tract-binding protein (Ptbp1). WebPolypyrimidine tract-binding protein (PTB) is an RNA-binding molecule that regulates mRNA splicing, polyadenylation, 3′ end formation, internal ribosomal entry site-mediated … flippingtraders.com
RNA-binding proteins and post-transcriptional gene regulation
WebInterestingly, the polypyrimidine strand of the repeat (CTC) bound other proteins such as polypyrimidine tract-binding protein 1 (PTBP1) as single-stranded (SS) DNA, and a model with two alternative DNA conformations is proposed for these repeats. Distinct protein binding to DS DNA was also observed for different numbers of AAACA and AAAAT repeats. WebMoreover, MALAT1 can also bind to the splicing factor proline/glutamine-rich (SFPQ) protein, contributing to dissociation of the SFPQ/polypyrimidine tract binding protein-2 (PTBP2) dimer, the release of PTBP2 and the increase of RUNX2 expression by interplaying with the IRES domain of the corresponding mRNA 5ʹUTR region. 49 WebLuc Buée is a European scientist (Directeur de Recherche au CNRS - DRCE CNRS), Director of the Lille Neuroscience & Cognition Research Centre and Head of the Inserm laboratory «Alzheimer & Tauopathies» at the University of Lille, France. Located on the Lille hospital campus, his laboratory belongs to the Lille Centre of Excellence in … greatest tank battles dvd